DINUTUXIMAB

Dinutuximabis a cancer medicine that works by interfering with the growth and spread of cancer cells in the body.

Dinutuximab is used in combination with other medicines to treat neuroblastoma (a type of brain tumor) in children.

Uses

This medication is used to treat a certain type of cancer (high-risk neuroblastoma). Dinutuximab is usually given after other treatments or medicines have been tried without success. It may also be used for purposes to be determined by your doctor.

Warnings

Do not use dinutuximab if you are pregnant.

Call your doctor at once if you have severe or worsening pain, numbness, tingling, weakness, or burning in your hands or feet, or if you have problems with walking or daily activities.

Some side effects may occur during the injection or up to 24 hours afterward. Tell your caregiver right away if you feel dizzy or light-headed, or if you have a skin rash, chest tightness, wheezing, trouble breathing, or swelling in your face.

Side Effects

Common side effects may include:

Nausea
Vomiting
Diarrhea
Dizziness or Lightheadedness

Tell your doctor or pharmacist promptly if any of these effects persist or worsen.

Serious side effects may include:

Mental/Mood Changes
Muscle Cramps/Spasms
Signs of Kidney Problems (such as Blood in the Urine, Change in the Amount of Urine)
Seizures
Signs of Infection (such as Persistent Sore Throat, Fever, Chills, Cough)

Rare side effects may include:

Capillary Leak Syndrome
Nerve Problem of the Eye/s
Serious Allergic Reaction

Precautions

Precautions

Before using Dinutuximab, tell your doctor or pharmacist:

If you are allergic to it; or if you have any other allergies.
Your medical history, especially of blood/bleeding problems and kidney problems.

Dinutuximab can make you more susceptible to infections or may worsen any current infections. Avoid contact with people who have contagious infections (such as chickenpox, measles, flu). If you have been exposed to an infection or for more details, consult your doctor.

Do not have immunizations/vaccinations without the consent of your doctor. Avoid contact with people who have recently received live vaccines (such as flu vaccine inhaled through the nose).

Interactions

Drug interactions may change how your medications work or increase your risk for serious side effects. Tell your doctor or pharmacist all prescription and non-prescription or herbal products you are using. Also, follow your doctor’s instructions about any restrictions on food, beverages, or activity.

Overdose & Brands

Call emergency hotline if someone has overdosed and has serious symptoms such as passing out or trouble breathing.