DINOPROSTONE

COMMON BRAND NAME(S): Cervidil

GENERIC NAME(S): DINOPROSTONE

 

Description: Dinoprostone causes induction of uterine muscle contraction during pregnancy. It is both a vasoconstrictor and bronchodilator.  It can also stimulate the smooth muscle of the GI tract.

Dinoprostone is a natural substance that your body makes in preparation for labor. It relaxes and softens your cervix (cervical ripening) to allow the baby to pass through the birth canal during delivery.

How to use dinoprostone vaginal

This drug is inserted high in your vagina next to the cervix by a health care professional.  This medication should only be used in a hospital setting with trained medical care available.

not available

Side effects such as fever, nausea, vomiting, diarrhea or abdominal pain are uncommon and usually mild. If these persist or worsen, notify your doctor or midwife immediately.

Other serious side effects include: strong contractions that are very close together (uterine overstimulation).

This drug has rarely caused injury to the womb (uterine rupture), which may require emergency surgery. Symptoms include severe pain in your womb and an abnormal heart rate in your baby. Your doctor or midwife will be monitoring for this and for signs of uterine overstimulation.

Allergic reaction is rare but must be treated promptly

Precautions

Before using this drug, tell your doctor of the current medications, products (herbal/nonprescription) that you are taking especially of: asthma, full term births including previous cesarean section (c-section) births, glaucoma, infections in the vaginal area (e.g., genital herpes), surgery on the cervix, surgery on the womb (uterus), vaginal bleeding during pregnancy, womb scarring.

It should not be used if you are carrying more than one baby, if your labor has already started, or if your water has broken.

 

Interactions

Some products that may interact with this drug include: other prostaglandins (such as, misoprostol), oxytocin.

Overdose

If overdose is suspected, contact a poison control center or emergency room immediately.

Storage

Store in a freezer between -4 and 14 degrees F (-20 to -10 degrees C) away from light and moisture.

Discard properly.

 

Brands

Available Brands

Propess [ Ferring ]

Also marketed as

Cerviprime [ AstraZeneca ]

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