DILTIAZEM HYDROCHLORIDE

Diltiazem is a calcium channel blocker. It works by relaxing the muscles of your heart and blood vessels.

Diltiazem is used to treat hypertension (high blood pressure), angina (chest pain), and certain heart rhythm disorders.

Do not give to patients with sick-sinus syndrome, pre-existing 2nd- or 3rd-degree AV block, marked bradycardia, acute myocardial infarction and pulmonary congestion, severe hypotension or cardiogenic shock.

Dizziness, lightheadedness, weakness, nausea, flushing, constipation, and headache may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.

To lower the risk of dizziness and lightheadedness, get up slowly when rising from a sitting or lying position.

Precautions

Before taking diltiazem, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: certain types of heart rhythm problems (such as sick sinus syndrome/atrioventricular block), liver disease, kidney disease, heart failure.

 

Interactions

Some products that may interact with this drug include: amiodarone, digoxin, fingolimod.

Other medications can affect the removal of diltiazem from your body, which may affect how this medication works. Examples include cimetidine, quinidine, St. John’s wort, azole antifungals such as ketoconazole, macrolide antibiotics such as erythromycin, rifamycins including rifabutin and rifampin.

Symptoms of overdose include hypotension, bradycardia, heart block, heart failure, impaired conduction, ECG changes, arrhythmias, shock, altered mental status, cardiac arrest. If overdose is suspected, bring the victim to the hospital immediately.

 

Available brands:

  • Angiozem (Littman)
  • Dilzem (Pfizer/Pharmalink)
  • RiteMED Diltiazem (RiteMED)

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