Clonorchis infection is caused by the liver fluke parasite clonorchis, which people may contract by consuming uncooked or raw fish from places where the parasite is present. Clonorchis, widespread throughout Asia, is also called the Oriental or Chinese liver fluke. Human liver flukes invade the bile duct, gallbladder, and liver. Although most infected people have no symptoms, long-term infections may cause severe symptoms and serious diseases.
Moreover, the swelling of the ducts and gallbladder induced by the parasite has been linked to the bile duct and liver malignancies, particularly cholangiocarcinoma, in places where liver flukes are widespread. An individual could have numerous long-standing uncontrolled liver fluke infections. Clonorchis infection is among the risk factors for cholangiocarcinoma.