Clarithromycin is a macrolide antibiotic that binds specifically to the 50S ribosomal subunit of susceptible bacteria, preventing the activation of amino acid transport, hence inhibiting intracellular protein production.

Use this medication precisely as recommended by your physician. Follow the prescription of your doctor carefully.

The medication dose your physician has given is based on your condition, other medications or food supplements you may take, and your reaction to treatment. To diminish your risks for adverse effects, don’t increase your dosage, take it regularly, or take it as instructed by your physician. Adverse events may still happen even at usual prescription dosages.

If your physician requests you to use this drug consistently, use it regularly to get the most benefits from it. To make you remember it better, take it at a fixed time every day.

Your doctor may need to modify your dosages to ease your symptoms or if you develop adverse reactions.

If you have any inquiries with regards to information, ask your physician or pharmacist.

Clarithromycin is used in the following conditions:

  • H. pylori eradication in patients with peptic ulcer disease
  • Infections caused by Mycobacterium Avium Complex (MAC)
  • Soft tissue and skin infections
  • Respiratory tract infections

This medicine may be recommended for different uses. Approach your physician or pharmacist for more information.

Do not use Clarithromycin in people with the following conditions:

  • Severe renal impairment (CrCl 30 mL/min)
  • Serious hepatic failure accompanied with renal insufficiency
  • Ventricular cardiac arrhythmia, including torsades de pointes
  • QT prolongation history
  • Hypokalemia
  • Previous clarithromycin usage that has been linked to hepatic impairment and cholestatic jaundice
  • Clarithromycin or any macrolide antibiotic hypersensitivity

Clarithromycin may have the following side effects:

  • Vasodilation (IV)
  • Hyperhidrosis
  • Rash
  • Insomia
  • Headache
  • Increased BUN
  • Prolonged prothrombin time
  • Candidiasis
  • Injection site reactions 
  • Dyspepsia
  • Dysgeusia
  • Vomiting
  • Nausea
  • Diarrhea
  • Abdominal pain
  • Exacerbation or new onset of myasthenia gravis
  • Hepatic dysfunction

Potentially Fatal: 

  • IgA vasculitis or Henoch-Schonlein purpura
  • Drug rash with eosinophilia and systemic symptoms
  • Toxic epidermal necrolysis
  • Stevens-Johnson syndrome
  • Acute generalized exanthematous pustulosis
  • Anaphylaxis
  • Arrhythmias
  • QT prolongation
  • C. Difficile-associated diarrhea (CDAD)
  • Pseudomembranous colitis 
  • Hepatic failure

Keep in mind that your physician has recommended this drug since he or she has known that the advantage to you is more noteworthy than the risk of adverse reactions. Many individuals utilizing this medicine don’t have serious side effects. 

A serious allergy to this medication is uncommon. In any case, seek emergency medical help if you see any manifestations of a serious allergic response, including a rash, tingling or swelling particularly of the face or tongue or throat, dizziness or difficulty in breathing.

This is not a complete list of side effects. If you see other effects not recorded above, contact your physician or pharmacist.

Take extra caution in patients with the following medical conditions:

  • Lactation
  • Pregnancy
  • Children
  • Hepatic and moderate to serious renal dysfunction
  • Patients with renal impairment receiving ritonavir or atazanavir- containing regimens at the same time
  • Patients using drug that is believed to lengthen the QT interval 
  • Myasthenia gravis
  • Hypomagnesaemia
  • Conduction disturbances
  • Clinically significant bradycardia
  • Serious heart failure
  • Patient suffering from coronary artery disease

Prior to taking this medicine, tell your physician or pharmacist if you are allergic to it, or if you have some other hypersensitivities. This drug may contain inert ingredients which can cause unfavorable side effects or different issues. Talk with your pharmacist for more information.


Clarithromycin may interact with the following medicines:

  • Triazolam
  • Diltiazem
  • Amlodipine
  • Verapamil
  • Saquinavir
  • Itraconazole
  • Atazanavi
  • Clarithromycin
  • Zidovudine
  • Disopyramide
  • Quinidine
  • Tolterodine
  • Valproate
  • Theophylline
  • Vinblastine
  • Tacrolimus
  • Sirolimus
  • Sildenafil
  • Quetiapine
  • Omeprazole
  • Methylprednisolone
  • Ciclosporin
  • Cilostazol
  • Arbamazepine
  • Alprazolam
  • Fluconazole
  • Etravirine
  • Rifapentine
  • Rifabutin
  • Nevirapine
  • Efavirenz
  • Phenobarbital
  • Carbamazepine
  • Phenytoin
  • Rifampicin
  • Warfarin
  • Insulin
  • Nateglinide
  • Repaglinide
  • Sulfonylureas

Potentially Fatal:

  • Ticagrelor
  • Ranolazine
  • Colchicine
  • Simvastatin
  • Lovastatin
  • Lomitapide
  • Oral midazolam
  • Dihydroergotamine
  • Ergotamine
  • Astemizole
  • Terfenadine
  • Domperidone
  • Pimozide
  • Cisapride

Inform your physician about the drugs you take including over-the-counter medications, prescribed drugs, supplements and vitamins.

This is not a complete list of drug interactions. Approach your physician or pharmacist for more details.

The effects of certain medications can change if you consume different medications or herbal products simultaneously. This can build your risk for side effects or may cause your drugs not to work effectively. These interactions are conceivable, yet don’t generally happen. Your physician or pharmacist can prevent or oversee interactions by changing how you utilize your prescriptions or by close checking.

While utilizing this drug, don’t start, stop, or change the dose of other medicines you are using without your physician’s advice.

Symptoms of overdose may include the following: 

  • Diarrhea
  • Nausea
  • Vomiting
  • Abdominal pain

Seek medical help immediately.

Available Brands:

  • RiteMED Clarithromycin
  • Klaz 250/Klaz Suspension
  • Klaryz
  • Klaryth
  • Klarimed
  • Klarid
  • Klaricid/Klaricid OD
  • Claryn
  • Claryl
  • Clarithro-Natrapharm Suspension
  • Clarithrocid
  • Clarimid
  • Clariget/Clariget OD
  • Clarie DS 125/Clarie DS 250

Related Articles


Kapirox-20 belongs to a class of medications known as nonsteroidal anti-inflammatory drugs (NSAIDs). It works by lowering hormones in the [...]


Juvenaid is a nutritious drink used to help exhausted individuals after surgery or who need to gain lean body mass. [...]


Juvelon E+ tablets include sodium fluoride and eleven vital vitamins in a chewable tablet form. Because the pills are chewable, [...]