CHRONIC MYELOID LEUKEMIA

Chronic myeloid leukemia is a rare kind of bone marrow (the layer of tissue within bones that produces blood cells) malignancy. Moreover, CML induces an increased number of WBC in the blood. It mainly affects elderly persons and rarely affects youngsters, while it may strike anybody at any age. Affected individuals now have a far better prognosis because of advanced therapy. After diagnosis, most individuals will undergo treatment and survive for many decades.

SYMPTOMS

Chronic myeloid leukemia symptoms are often unclear and are more typically caused by other factors. When they develop, you could notice the following:

  • Impairment
  • Exhaustion
  • Night sweats
  • Loss of weight
  • Fever
  • Bone pain
  • Fullness or pain below the ribs
  • Feeling satiated with just a tiny quantity of food

However, they aren’t simply Chronic myeloid leukemia symptoms. They may occur with different malignancies and a variety of non-cancerous diseases. So, make sure to make an appointment with your healthcare provider for further assessment.

DIAGNOSIS

Chronic myeloid leukemia is diagnosed using the tests and procedures listed below:

  • Physical examination. The medical provider examines you and checks vital signs such as blood pressure and heart rate. 
  • Blood testing. A complete blood count might detect irregularities in the blood cells, including abnormally high white blood cells. Blood chemistry testing used to assess body functions may show anomalies that might aid your doctor in making a diagnosis.
  • Bone marrow testing. Bone marrow resection and bone marrow extraction are utilized to analyze bone marrow specimens. Bone marrow from the hipbone is collected for these examinations.
  • Philadelphia chromosome testing. Plasma or bone marrow specimens are analyzed using the Philadelphia chromosome using special examinations.

TREATMENT

People with chronic myeloid leukemia might receive a variety of treatments. Some therapies are mainstream (already in use), while others undergo clinical testing. 

  • Targeted drug therapy. Medications or other chemicals that detect and kill individual cancer cells in this sort of therapy.
  • Chemotherapy. A cancer therapy that uses medicines to inhibit the proliferation of cancer cells by eliminating or preventing them from reproducing.
  • Immunotherapy. A cancer-fighting therapy that makes use of the patient’s immune response.
  • Stem cell transplant. Cancer cells are killed with high dosages of chemotherapy. Cancer therapy also destroys healthy tissue, such as blood-forming molecules.
  • Donor lymphocyte infusion (DLI). Following a stem cell transplant, this cancer therapy may be employed.

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