Chlorpromazine

Chlorpromazine is a prototype phenothiazine antipsychotic drug that blocks the postsynaptic dopamine receptors in the mesolimbic dopaminergic system and inhibits the release of hypothalamic and hypophyseal hormones. It has sedative and antiemetic properties, slight ganglion-blocking activities, serotonin-blocking activities and weak antihistamine and anticholinergic properties.

Use this medication precisely as recommended by your physician. Follow the prescription of your doctor carefully.

The medication dose given by your physician is based on your health conditions, other medications or food supplements taken, and your reaction to the treatment. To diminish risks for adverse effects, do not increase your dosage, thus take it regularly, or take it as instructed by your physician. Adverse events may still happen even at usual prescription dosages.

If your physician requests you to use this drug consistently, take it regularly to get the most benefits from it. To make you remember it better, take it at a fixed time every day.

Your doctor may need to modify your dosages to ease your symptoms or if you develop adverse reactions.

If you have any inquiries with regards to information, ask your physician or pharmacist.

Uses

Chlorpromazine is used in the following conditions:

Intractable hiccups
Psychoses
Nausea
Vomiting

This medicine may be recommended for different uses. Approach your physician or pharmacist for more information.

Warnings

Do not use Chlorpromazine in people with the following conditions:

Hypersensitivity
Pre-existing central nervous systemdepression
Coma
Bone-marrow suppression
Pheochromocytoma
Lactation

Side Effects

Chlorpromazine may have the following side effects:

Tardive dyskinesia (on long-term therapy)
Involuntary movements of extremities may also occur
Dry mouth
Constipation
Urinary retention
Mydriasis
Agitation
Insomnia
Depression
Convulsions
Postural hypotension
Electrocardiogramchanges
Allergic skin reaction
Amenorrhea
Gynecomastia
Weight gain
Hyperglycemia
Raised serum cholesterol

Potentially Fatal:

Agranulocytosis
Instantaneous deaths associated with ventricular tachyarrhythmias
Marked elevation of body temperature with heat stroke
Neuroleptic malignant syndrome
Extrapyramidal dysfunction

Keep in mind that your physician has recommended this drug since he or she has known that the advantage to you is more significant than the risk of adverse reactions. Many individuals utilizing this medicine don’t have serious side effects.

A severe allergy to this medication is uncommon. In any case, seek emergency medical help if you see any manifestations of a serious allergic response, including a rash, tingling or swelling particularly of the face or tongue or throat, dizziness or difficulty in breathing.

This is not a complete list of side effects. If you see other effects not recorded above, contact your physician or pharmacist.

Precautions

Take extra caution in patients with the following medical conditions:

Parkinson’s disease
Cardiovasculardisease
Renal or hepatic impairment
Cerebrovascular and respiratorydisease
Jaundice
Diabetes mellitus
Hypothyroidism
Paralytic ileus
Prostatic hyperplasia or urinary retention
Epilepsy or history of seizures
Myasthenia gravis
Pregnancy
Elderly (especially with dementia)
Debilitated patients
Avoid direct sunlight

Prior in taking this medicine, tell your physician or pharmacist if you have allergies or other hypersensitivity reactions with the drug. This drug may contain inert ingredients which can cause unfavorable side effects or different issues. Talk with your pharmacist for more information.

Interactions

Chlorpromazine may interact with the following medicines:

Monoamine oxidase inhibitors
Guanethidine
Methyldopa
Clonidine
Sedatives
Hypnotics
Antihistamines
General anaesthetics
Opiates
Alcohol

Inform your physician about the drugs you take including over-the-counter medications, prescribed drugs, supplements and vitamins.

This is not a complete list of drug interactions. Approach your physician or pharmacist for more details.

The effects of certain medications can change if you consume different medications or herbal products simultaneously. This can build your risk for side effects or may cause your drugs not to work effectively. These interactions are possible, yet don’t generally happen. Your physician or pharmacist can prevent or oversee interactions by changing how you utilize your prescriptions or by close checking.

While utilizing this drug, don’t start, stop, or change the dose of other medicines you are using without your physician’s advice.

Overdose & Brands

If you think you have used Chlorpromazine more than the usual dosage, please seek medical help immediately.

Symptoms of overdose may include the following:

Somnolence
Coma
Hypotension
Extrapyramidal symptoms
Agitation
Restlessness
Convulsions
Fever
Autonomic reactions such as dry mouth and ileus
Electrocardiogramchanges
Cardiac arrhythmias

Available Brands:

Laractyl
Psynor
Zycloran
Proma
Promazine
Globazine
Harson Chlorpromazine