CERTOLIZUMAB PEGOL

Certolizumab pegol is a drug that is used to treat arthritis. It is a pegylated tumor necrosis factor (TNF) antibody that attaches to TNF-alpha, which is a cytokine that triggers inflammatory reactions. It likewise represses the formation of lipopolysaccharide-activated TNF-alpha and interleukin-1beta (IL-1β).

Use this medication precisely as recommended by your physician. Follow the prescription of your doctor carefully.

The medication dose your physician has given is based on your condition, other medications or food supplements you may take, and your reaction to treatment. To diminish your risks for adverse effects, don’t increase your dosage, take it regularly, or take it as instructed by your physician. Adverse events may still happen even at usual prescription dosages.

If your physician requests you to use this drug consistently, use it regularly to get the most benefits from it. To make you remember it better, take it at a fixed time every day.

Your doctor may need to modify your dosages to ease your symptoms or if you develop adverse reactions.

If you have any inquiries with regards to information, ask your physician or pharmacist.

Uses

Certolizumab pegol is used in the following conditions:

Moderate to severe rheumatoid arthritis
Psoriatic arthritis

This medicine may be recommended for different uses. Approach your physician or pharmacist for more information.

Warnings

Do not use Certolizumab pegol in people with the following conditions:

Active infection
Chronic or localized infections (e.g. active TB)
Moderate or severe heart failure (NYHA class III/IV)
Those using Anakinra, Abataceptor live vaccines

Side Effects

Certolizumab pegol may have the following side effects:

Antinuclear antibody formation
Immunogenicity
Immunosuppression
Seizure disorder
Peripheral neuropathy
Multiple sclerosis
Guillain-Barre syndrome
Optic neuritis
Pancytopenia
Aplastic anaemia
Leucopenia
Thrombocytopenia
Severe hypersensitivity
Lupus-like syndrome
Hypercoagulopathy
Atrial fibrillation
Angina pectoris
Cardiac arrhythmia
Hypertensive heart disease
Ischemic heart disease
Pericarditis
Pericardial effusion
Retinal hemorrhage
Nausea
Fatigue
Fever
Hepatitis
Urticaria
Erythema nodosum
Bacterial (e.g. abscess)infections
Viral (e.g. influenza) infections
Elevated hepatic transaminases
Arthralgia
Back pain
Headache
Dizziness
Anxiety
Bipolar disorder
Suicidal tendencies
Urinary tract infection
Nephrotic syndrome
Renal failure
Menstrual disease
Upper respiratory tract infection
Cough
Alopecia
Dermatitis
Hypertension
Vasculitis
Hemorrhage
Serious infections
Sepsis
Tuberculosis
Invasive fungal, bacterial or viral infections
Hepatitis B virus (HBV) reactivation (in chronic HBV virus carriers)
Exacerbation of or new onset CHF
Lymphoma
Leukemia
Melanoma
Merkel cell carcinoma

Keep in mind that your physician has recommended this drug since he or she has known that the advantage to you is more noteworthy than the risk of adverse reactions. Many individuals utilizing this medicine don’t have serious side effects.

A serious allergy to this medication is uncommon. In any case, seek emergency medical help if you see any manifestations of a serious allergic response, including a rash, tingling or swelling particularly of the face or tongue or throat, dizziness or difficulty in breathing.

This is is not a complete list of side effects. If you see other effects not recorded above, contact your physician or pharmacist.

Precautions

Take extra caution in patients with the following medical conditions:

Hematologic disorders
Hypersensitivity reactions (e.g. rash, angioedema, urticaria, dyspnea, hypotension)
Mild heart failure (NYHA class I/II)
Pre-existing or recent central or peripheral nervous system demyelinating disorders
Latent tubercu;osis
Chronic hepatitis B virus (HBV) carriers
History of chronic, recurrent or opportunistic infections
Malignancy (including history of)
Risk factors for skin cancer
Undergoing surgery
Exposed to tuberculosis
Pregnancy
Lactation

Prior to taking this medicine, tell your physician or pharmacist if you are allergic to it, or if you have some other hypersensitivities. This drug may contain inert ingredients which can cause unfavorable side effects or different issues. Talk with your pharmacist for more information.

Interactions

Certolizumab pegol may interact with the following medicines:

Anakinra
Abatacept
Live vaccines

Inform your physician about the drugs you take including over-the-counter medications, prescribed drugs, supplements and vitamins.

This is not a complete list of drug interactions. Approach your physician or pharmacist for more details.

The effects of certain medications can change if you consume different medications or herbal products simultaneously. This can build your risk for side effects or may cause your drugs not to work effectively. These interactions are conceivable, yet don’t generally happen. Your physician or pharmacist can prevent or oversee interactions by changing how you utilize your prescriptions or by close checking.

While utilizing this drug, don’t start, stop, or change the dose of other medicines you are using without your physician’s advice.

Overdose & Brands

If overdose is suspected call your health care provider immediately.

Available Brand:

Cimzia