BUDESONIDE ORAL

GENERIC NAME(S): BUDESONIDE

COMMON BRAND NAME(S): Entocort EC

 

Description

  • An anti-inflammatory drug (corticosteroid hormone) that works by decreasing the body’s natural defense response (immune response)
  • For certain bowel conditions, such as Crohn’s disease or ulcerative colitis
    • does not cure these conditions, but may decrease symptoms such as pain and diarrhea

How to use budesonide

  • Take by mouth with or without food and with a full glass of water as directed by your doctor, usually once daily in the morning. Swallow this medication whole. Do not crush or chew. (can release all of the drug at once, increasing the risk of side effects)
    • If you are using the extended-release tablets, do not split the tablets unless they have a score line and your doctor or pharmacist tells you to do so. Swallow the whole or split tablet without crushing or chewing.
  • The dosage and length of treatment are based on your medical condition and response to treatment.
  • Avoid eating grapefruit or drinking grapefruit juice while being treated with this medication unless your doctor instructs you otherwise.
  • May increase the amount of certain medications in your body
  • If you are regularly taking a different corticosteroid by mouth (such as prednisone), you should not stop taking it unless directed by your doctor. Some conditions (such as asthma, allergies) may become worse when the drug is suddenly stopped. You may have withdrawal symptoms if the drug is suddenly stopped. To prevent withdrawal symptoms (such as weakness, weight loss, nausea, muscle pain, headache, tiredness, dizziness), your doctor may direct you to slowly lower the dose of your old medication when you are taking budesonide.
  • Use this medication regularly and exactly as prescribed in order to get the most benefit from it. To help you remember, use it at the same time each day. Do not increase your dose, take it more frequently, or use it for a longer time than prescribed because this may increase your risk of serious side effects.
  • Do not stop taking this medication without consulting your doctor. Some conditions may become worse when this drug is suddenly stopped. Your dose may need to be gradually decreased.
  • Inform your doctor if your condition persists or worsens.

Not available.

  • Usually has fewer side effects than other corticosteroids because it works in the gut and only small amounts are absorbed into the body.
  • Minor side effects (if these symptoms persist or worsen, inform your doctor)
    • Nausea, heartburn, and headache
    • Because this drug works by weakening the immune system, it may lower your ability to fight infections. This may make you more likely to get a serious (rarely fatal) infection or make any infection you have worse. Tell your doctor right away if you have any signs of infection (such as cough, sore throat, fever, chills). Use of this medication for prolonged or repeated periods may result in oral thrush or a yeast infection. Contact your doctor if you notice white patches in your mouth or a change in vaginal discharge.
  • Serious side effects (inform your doctor immediately)
    • unusual tiredness, vision problems, easy bruising/bleeding, puffy face, unusual hair growth, mental/mood changes (such as depression, mood swings, agitation), muscle weakness/pain, thinning skin, slow wound healing
  • Severe allergic reactions are rare. Get immediate medical help if you notice the following:
    • Rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing

Precautions

  • Inform your doctor
    • Allergy to the medication or any allergies
    • Medical History, espescially of:
      • eye disease (such as cataracts, glaucoma), high blood pressure, liver disease, thyroid problems, diabetes, stomach/intestinal problems (such as diverticulitis, ulcer), brittle bones (osteoporosis), current/past infections (such as tuberculosis, positive tuberculosis test, herpes, fungal), bleeding problems, mental/mood conditions (such as psychosis, anxiety, depression)
  • Before having surgery or emergency treatment, or if you get a serious illness/injury, tell your doctor or dentist that you are using this medication or have used this medication within the past 12 months. Tell your doctor right away if you develop unusual/extreme tiredness or weight loss. If you will be using this medication for a long time, carry a warning card or medical ID bracelet that identifies your use of this medication.
  • Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products
  • Daily use of alcohol while using this medicine may increase your risk for stomach bleeding. Limit alcoholic beverages.
  • May mask signs of infection and/or make you more likely to get infections or may worsen any current infections.
  • Practice proper handwashing to prevent the spread of infection. Avoid contact with people who have infections that may spread to others (such as chickenpox, measles, flu)
  • May cause vaccines not to work as well.
  • Do not have any immunizations/vaccinations while using this medication without the consent of your doctor. Avoid contact with people who have recently received live vaccines (such as flu vaccine inhaled through the nose)
  • May slow down a child’s growth if used for a long time. Consult the doctor or pharmacist for more details. See the doctor regularly so your child’s height and growth can be checked.
  • During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor. Babies born to mothers who have used corticosteroids for a long time may develop hormone problems. Tell your doctor right away if you notice symptoms such as persistent nausea/vomiting, severe diarrhea, or weakness in your newborn.
  • Passes into breast milk. Consult your doctor before breast-feeding.

 

Interactions

Taking multiple drugs may affect how medications work and/or cause unwanted side effects. List down all the medications you are taking and inform your physician and pharmacist. Do not take, discontinue, or alter any dose of medications without prior approval of your physician.

  • Products that may interact with this medication include:
    • aldesleukin, mifepristone, drugs that can cause bleeding/bruising (including antiplatelet drugs such as clopidogrel, “blood thinners” such as dabigatran/warfarin, NSAIDs such as aspirin/celecoxib/ibuprofen).
  • If your doctor has directed you to take low-dose aspirin for heart attack or stroke prevention (usually at dosages of 81-325 milligrams a day), you should continue taking it unless your doctor instructs you otherwise. Ask your doctor or pharmacist for more details.
  • Labratory tests that may be affected:
    • skin tests

Overdose

If overdose is suspected, contact a poison control center or emergency room immediately.

  • If used for an extended time, laboratory and/or medical tests (such as blood count, bone density tests, eye exams, height/weight measurements) should be performed regularly to check for side effects. Consult your doctor for more details.
  • May cause bone problems (osteoporosis)
  • Lifestyle changes that may help reduce the risk of bone problems while taking this drug for an extended time include doing weight-bearing exercise, getting enough calcium and vitamin D, stopping smoking, and limiting alcohol

Missed Dose

If you miss a dose, take it as soon as you remember. If it is near the time of the next dose, skip the missed dose and as soon as you remember, take a regular dose or if the time of the next dose is near, wait for it before taking another dose and resume your usual schedule. Do not increase the dose to compensate for the missed dose.

Storage

  • Room temperature
  • Do not expose to light and moisture
  • Do not store in the bathroom
  • Keep all medications away from pets and children
  • Do not flush medications down the toilet or pour them into a drain unless instructed to do so
  • Properly discard this product when it is expired or no longer needed

Consult your pharmacist or local waste disposal company for more details about how to safely discard your product.

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