BRINZOLAMIDE + TIMOLOL

Brinzolamide inhibits carbonic anhydrase in the ciliary process of the eye, resulting in less aqueous humour discharge and lower intraocular pressure. Timolol is a -adrenergic receptor blocker that is nonselective. It lowers intraocular pressure by inhibiting the production of aqueous humour and perhaps enhancing sympathetic outflow.

Use this medication precisely as recommended by your physician. Follow the prescription of your doctor carefully.

The medication dose given by your physician is based on your health conditions, other medications or food supplements taken, and your reaction to the treatment. To diminish risks for adverse effects, do not increase your dosage, thus take it regularly, or take it as instructed by your physician. Adverse events may still happen even at usual prescription dosages.

If your physician requests you to use this drug consistently, take it regularly to get the most benefits from it. To make you remember it better, take it at a fixed time every day.

Your doctor may need to modify your dosages to ease your symptoms or if you develop adverse reactions.

Uses

Brinzolamide + Timolol is used in the following conditions:

Ocular hypertension
Open-angle glaucoma

This medicine may be recommended for different uses. Approach your physician or pharmacist for more information.

Warnings

Do not use Brinzolamide + Timolol in people with the following conditions:

Hypersensitivity to brinzolamide, timolol, or sulfonamides
Current or history of bronchial asthma
Severe chronic obstructive pulmonary disease (COPD)
Sinus bradycardia
Sick sinus syndrome
Sino-atrial block
2nd or 3rd degree atrioventricular block
Overt cardiac failure
Cardiogenic shock
Severe allergic rhinitis
Hyperchloremic acidosis
Severe renal impairment (creatinine clearance less than 30 mL/min)

Side Effects

Brinzolamide + Timolol may have the following side effects:

Bacterial keratitis
Impairment of mental alertness and/or physical coordination
Decreased heart rate
Blurred vision
Eye irritation
Eye pain
Foreign body sensation of eye
Punctate keratitis
Dysgeusia

Keep in mind that your physician has recommended this drug since he or she has known that the advantage to you is more significant than the risk of adverse reactions. Many individuals utilizing this medicine don’t have serious side effects.

A severe allergy to this medication is uncommon. In any case, seek emergency medical help if you see any manifestations of a serious allergic response, including a rash, tingling or swelling particularly of the face or tongue or throat, dizziness or difficulty in breathing.

This is not a complete list of side effects. If you see other effects not recorded above, contact your physician or pharmacist.

Precautions

Take extra caution in patients with the following medical conditions:

Coronary heart disease
Prinzmetal angina
Cardiac failure
1st degree heart block
Hypotension
Diabetes mellitus
Myasthenia gravis
Peripheral vascular disease (PVD)
Raynaud’s disease
History of psychiatric illness
Mild to moderate chronic obstructive pulmonary disease (COPD)
Thyrotoxicosis
Corneal diseases
History of atopy or severe anaphylactic reaction to allergens
Narrow-angle glaucoma
Severe hepatic impairment
Mild to moderate renal impairment
Pregnancy
Lactation

Prior in taking this medicine, tell your physician or pharmacist if you have allergies or other hypersensitivity reactions with the drug. This drug may contain inert ingredients which can cause unfavorable side effects or different issues. Talk with your pharmacist for more information.

Interactions

Brinzolamide + Timolol may interact with the following medicines:

Brinzolamide:

Carbonic anhydrase inhibitors
Ketoconazole
Ritonavir

Timolol:

Calcium channel blockers
βeta-adrenergic blocking agents
Amiodarone
Digitalis glycosides
Parasympathomimetics
Guanethidine
Quinidine
Cimetidine
Antidiabetic agents
Epinephrine

Inform your physician about the drugs you take including over-the-counter medications, prescribed drugs, supplements and vitamins.

This is not a complete list of drug interactions. Approach your physician or pharmacist for more details.

The effects of certain medications can change if you consume different medications or herbal products simultaneously. This can build your risk for side effects or may cause your drugs not to work effectively. These interactions are possible, yet don’t generally happen. Your physician or pharmacist can prevent or oversee interactions by changing how you utilize your prescriptions or by close checking.

While utilizing this drug, don’t start, stop, or change the dose of other medicines you are using without your physician’s advice.

Overdose & Brands

If an overdose is suspected, call your health care provider immediately.

Available brands:

Azarga