Biliary atresia, extrahepatic is an uncommon gastrointestinal illness marked by the damage or absence of all or part of the bile duct outside the liver (extrahepatic bile duct). The bile duct makes a connection to the liver towards the gallbladder, which then connects to the small intestine.
Bile is a liquid generated by the liver responsible for transporting waste products from the liver and facilitating fat and vitamin absorption by the intestines. Because bile ducts are lacking or disrupted in biliary atresia, bile accumulates abnormally in the liver. Affected infants’ skin and the whites of their eyes turn yellowish (jaundice), and they develop liver scars (fibrosis). Additional abnormalities, such as heart problems and intestine, spleen, and renal anomalies, may be present in rare cases. Furthermore, there is no known cause for biliary atresia.