Common side effects:
- dry mouth
- cough
- voice changes
- loss of appetite
- diarrhea
- vomiting
- constipation
- mouth sores
- nausea
- headache
Tell your doctor right away if you have any serious side effects, including: swelling of ankles/feet, sudden weight gain, fast heartbeat, signs of infection (e.g., fever, persistent sore throat), muscle cramps, muscle loss, yellowing eyes/skin, frothy/dark urine, difficulty urinating, decreased amount of urine.
Symptoms of a severe infusion reaction that may occur during bevacizumab treatment include:
- difficulty breathing
- flushing
- severe dizziness
- nausea/vomiting
- shaking
- chest pain
Bevacizumab may rarely cause blood clots (such as pulmonary embolism, stroke, heart attack, deep vein thrombosis). You may be at increased risk for blood clots if you have a history of blood clots, heart/blood vessel disease, or if you are immobile (such as on very long plane flights or being bedridden). If you use estrogen-containing products, these may also increase your risk.
This medication can cause bleeding. Some episodes may be minor including nosebleeds, minor gum bleeding, and vaginal bleeding. If these persist or worsen, notify your doctor or pharmacist promptly. Other episodes may be more serious including stomach bleeding or bleeding in the lungs
This medication may raise your blood pressure. Check your blood pressure regularly and tell your doctor if the results are high. Your doctor may control your blood pressure with medication.
Rarely, bevacizumab may cause a condition called PRES (posterior reversible encephalopathy syndrome). Get medical help right away if you develop persistent headache, seizures, sudden vision changes, mental/mood changes (e.g., confusion).
This medication may affect the ovaries, possibly reducing fertility and causing hormone changes. Talk to your doctor for more details.