HUMAN PAPILLOMAVIRUS 9-VALENT VACCINE

BEPRIDIL

During depolarization, Bepridil blocks calcium ions from accessing the slow channels of vascular smooth muscle and myocardium, thereby inducing coronary vascular smooth muscle relaxation and coronary vasodilatation. Fast (inward) sodium channels can also be blocked, which may account for some of its side effects; a direct bradycardia effect has been postulated on the SA node by direct action.

Use this medication precisely as recommended by your physician. Follow the prescription of your doctor carefully.

The medication dose given by your physician is based on your health conditions, other medications or food supplements taken, and your reaction to the treatment. To diminish risks for adverse effects, do not increase your dosage, thus take it regularly, or take it as instructed by your physician. Adverse events may still happen even at usual prescription dosages.

If your physician requests you to use this drug consistently, take it regularly to get the most benefits from it. To make you remember it better, take it at a fixed time every day.

Your doctor may need to modify your dosages to ease your symptoms or if you develop adverse reactions.

Bepridil is used in the following conditions:

  • Angina pectoris

This medicine may be recommended for different uses. Approach your physician or pharmacist for more information.  

Do not use Bepridil in people with the following conditions:

  • Hypersensitivity
  • History of serious ventricular or atrial arrhythmias
  • Decompensated cardiac insufficiency
  • Congenital QT interval prolongation

Bepridil may have the following side effects:

  • Dizziness
  • Nausea
  • Dyspnea
  • Bradycardia
  • Edema
  • Palpitations
  • QT prolongation
  • Congestive Heart Failure
  • Nervousness
  • Headache
  • Drowsiness
  • Psychiatric disturbances
  • Insomnia
  • Rash
  • Sexual dysfunction
  • GI disturbances
  • Weakness
  • Tremor
  • Paresthesia
  • Blurred vision
  • Tinnitus
  • Rhinitis
  • Dyspnea
  • Cough
  • Flu syndrome
  • Diaphoresis
  • Akathisia
  • Arrhythmia
  • Leukopenia
  • Neutropenia
  • Ventricular torsade de pointes

Keep in mind that your physician has recommended this drug since he or she has known that the advantage to you is more significant than the risk of adverse reactions. Many individuals utilizing this medicine don’t have serious side effects.  

A severe allergy to this medication is uncommon. In any case, seek emergency medical help if you see any manifestations of a serious allergic response, including a rash, tingling or swelling particularly of the face or tongue or throat, dizziness or difficulty in breathing.

This is not a complete list of side effects. If you see other effects not recorded above, contact your physician or pharmacist.

Precautions

Take extra caution in patients with the following medical conditions:

  • Lactation
  • Pregnancy
  • History of idiopathic hypertrophic subaortic stenosis
  • 2nd or 3rd ° Atrioventricular block
  • Cardiogenic shock
  • Congestive Heart Failure
  • Significant hypotension
  • Severe left ventricular dysfunction
  • Hypertrophic cardiomyopathy (especially obstructive)
  • Concomitant therapy with beta-blockers or digoxin
  • Edema
  • Increased intracranial pressure with cranial tumors
  • Elderly
  • Children below 18 years old
  • Impaired renal or hepatic function
  • Abrupt withdrawal may cause chest pain
  • Avoid use in patients in the immediate period postinfarction

Prior in taking this medicine, tell your physician or pharmacist if you have allergies  or other hypersensitivity reactions with the drug. This drug may contain inert ingredients which can cause unfavorable side effects or different issues. Talk with your pharmacist for more information.

Interactions

Bepridil may interact with the following medicines:

  • CYP206 enzyme
  • H2-blocker
  • Beta-blockers 
  • Carbamazepine
  • Ciclosporin
  • Digitalis
  • Quinidine
  • Theophylline
  • Fentanyl

Potentially Fatal: 

  • Amprenavir
  • Ritonavir
  • Sparfloxacin
  • Gatifloxacin
  • Moxifloxacin
  • Ritonavir
  • Amprenavir
  • Sparfloxacin
  • Cisapride

Inform your physician about the drugs you take including over-the-counter medications, prescribed drugs, supplements and vitamins.

This is not a complete list of drug interactions. Approach your physician or pharmacist for more details.

The effects of certain medications can change if you consume different medications or herbal products simultaneously. This can build your risk for side effects or may cause your drugs not to work effectively. These interactions are possible, yet don’t generally happen. Your physician or pharmacist can prevent or oversee interactions by changing how you utilize your prescriptions or by close checking.

While utilizing this drug, don’t start, stop, or change the dose of other medicines you are using without your physician’s advice.

If an overdose is suspected, call your health care provider immediately.

Available brands:

  • Vascor

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