Atropine is an anticholinergic drug that inhibits acetylcholine interaction with muscarinic receptors in the peripheral tissues and central nervous system, including the secretory glands, iris, bronchial muscles, gut, and heart. Atropine eliminates bradycardia by decreasing vagal activity, thus raising heart rhythm. It also increases bronchodilation by reducing respiratory system fluids and calming the bronchial smooth muscles. By paralyzing the ciliary muscles and suppressing circular pupillary sphincter muscular contraction necessary for adjustment, topical atropine on the eyes causes cycloplegia and mydriasis.


Use this medication precisely as recommended by your physician. Follow the prescription of your doctor carefully. 

The medication dose your physician has given is based on your condition, other medications or food supplements you may take, and your reaction to treatment. To diminish your risks for adverse effects, don’t increase your dosage, take it regularly, or take it as instructed by your physician. Adverse events may still happen even at usual prescription dosages. 

If your physician requests you to use this drug consistently, use it regularly to get the most benefits from it. To make you remember it better, take it at a fixed time every day. 

Your doctor may need to modify your dosages to ease your symptoms or if you develop adverse reactions.

If you have any inquiries with regards to information, ask your physician or pharmacist.

Atropine is used in the following conditions:


  • Non-ulcer dyspepsia
  • Irritable bowel syndrome
  • Diverticular disease
  • Uveitis
  • Iritis
  • Mydriasis and cycloplegia for refraction
  • Bradycardia
  • Organophosphorus poisoning


This medicine may be recommended for different uses. Approach your physician or pharmacist for more information.

Do not use Atropine in people with the following conditions:


  • Lactation (IV)
  • Myasthenia gravis
  • Obstructive uropathy
  • Prostatic hypertrophy
  • Pyloric stenosis
  • Toxic megacolon
  • Intestinal atony
  • Narrow angle between the cornea and iris
  • Extreme ulcerative colitis
  • Paralytic ileus
  • 2nd or 3rd degree AV block, achalasia of the esophagus
  • Angle-closure glaucoma

Atropine may have the following side effects:


  • Flushing
  • Dermatitis
  • Rash
  • Anhidrosis
  • Laryngitis
  • Decreased bronchial secretion
  • Dyspnoea
  • Urinary urgency
  • Tachycardia
  • Transient bradycardia
  • Pulmonary edema
  • Urinary retention
  • Delirium
  • Agitation
  • Amnesia
  • Insomnia
  • Disorientation
  • Hallucinations
  • Confusion
  • Headache
  • Dizziness
  • Restlessness
  • Dysgeusia
  • Hyperglycaemia
  • Hypokalaemia
  • Increased thirst
  • ECG changes
  • Abnormal EEG
  • Increased intraocular pressure
  • Irregular pulse
  • Ataxia
  • Asthenia
  • Irritability
  • Fever
  • Vomiting
  • Nausea
  • Constipation
  • Dysphagia
  • Dry mouth
  • Reduced lacrimation
  • Chest pain
  • Palpitations
  • Seizures
  • Hypertensive crisis 
  • Photophobia


Keep in mind that your physician has recommended this drug since he or she has known that the advantage to you is more noteworthy than the risk of adverse reactions. Many individuals utilizing this medicine don’t have serious side effects.  

A serious allergy to this medication is uncommon. In any case, seek emergency medical help if you see any manifestations of a serious allergic response, including a rash, tingling or swelling particularly of the face or tongue or throat, dizziness or difficulty in breathing. 

This is is not a complete list of side effects. If you see other effects not recorded above, contact your physician or pharmacist.

Take extra caution in patients with the following medical conditions:

  • Patients who have a fever or have been subjected to a high ambient temperature
  • Hepatic and renal impairment
  • Children
  • Cardiac surgery
  • Pregnancy 
  • Lactation
  • Hypertension
  • Myocardial ischemia
  • Heart failure
  • COPD
  • Diarrhea
  • GERD
  • Gastric ulcers
  • Hyperthyroidism
  • Hiatal hernia
  • Spastic paralysis
  • Increased intraocular pressure
  • Autonomic neuropathy
  • Brain damage
  • Patients with Down’s syndrome


Prior to taking this medicine, tell your physician or pharmacist if you are allergic to it, or if you have some other hypersensitivities. This drug may contain inert ingredients which can cause unfavorable side effects or different issues. Talk with your pharmacist for more information.




Atropine may interact with the following medicines:

  • Cholinomimetic alkaloids
  • Anticholinesterase drugs
  • Mexiletine
  • Antihistamines
  • Antipsychotics
  • MAOIs
  • TCA
  • Anticholinergics
  • Antiarrhythmics
  • Amantadine


Inform your physician about the drugs you take including over-the-counter medications, prescribed drugs, supplements and vitamins. 

This is not a complete list of drug interactions. Approach your physician or pharmacist for more details. 

The effects of certain medications can change if you consume different medications or herbal products simultaneously. This can build your risk for side effects or may cause your drugs not to work effectively. These interactions are conceivable, yet don’t generally happen. Your physician or pharmacist can prevent or oversee interactions by changing how you utilize your prescriptions or by close checking. 

While utilizing this drug, don’t start, stop, or change the dose of other medicines you are using without your physician’s advice.

Symptoms of overdose may include the following: 

  • Seizures
  • Delirium
  • Vomiting
  • Nausea 
  • Drowsiness
  • Dizziness
  • Blurred vision
  • Dry throat
  • Dry nose 
  • Dry mouth
  • Tachycardia
  • Increased respiratory rate
  • Hypertension
  • Hyperthermia

Seek medical help immediately. 

Available Brands:

  • Isopto Atropine
  • Atropa

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