ATENOLOL

  • Bradycardia, hypotension, chest pain, oedema, heart failure. Dizziness, sweating, fatigue, insomnia, lethargy, confusion, mental impairment, depression, headache, nightmares. Constipation, diarrhoea, nausea, impotence, cold extremities.

PRECAUTIONS

  • Should not be used in patients with the following conditions:
    • Sick sinus syndrome, severe bradycardia, 2nd or 3rd degree AV block, uncompensated cardiac failure, severe asthma or COPD, cardiogenic shock, untreated pheochromocytoma, metabolic acidosis, severe peripheral circulatory disease.
  • Caution for use in patients with w/ inadequate cardiac function, well-compensated heart failure, bronchospastic disease, DM, hyperthyroidism.
  • If you are planning to be pregnant or think you may be pregnant, discuss the risks and benefits of use with your doctor.
  • Before breast-feeding, consult your physician.

 

INTERACTIONS

Taking multiple drugs may affect how medications work and/or cause unwanted side effects. List down all the medications you are taking and inform your physician and pharmacist. Do not take, discontinue, or alter any dose of medications without prior approval of your physician.

  • Products that may interact with this medication include:
    • Reserpine, Ca channel blockers, hydralazine, methyldopa, verapamil and diltiazem, NSAIDs (e.g. indometacin), disopyramide, amiodarone or digitalis glycosides, clonidine and orange juice.

STORAGE

Store between 20-25°C

DOSAGE

  • Adult: By mouth; May be taken with or without food.
    • HTN 25-100 mg once daily. Angina pectoris 50-100 mg/day in single or divided doses. Max: 200 mg/day.
    • IV Emergency treatment of cardiac arrhythmias 2.5 mg at a rate of 1 mg/min. May repeat every 5 min if needed. Max: 10 mg. Switch to oral therapy 50-100 mg/day once control is achieved.
    • Acute MI 5-10 mg via slow injection w/in 12 hr of the onset of chest pain, then an oral dose of 50 mg 15 min later.

 

OVERDOSAGE

If overdose is suspected, contact a poison control center or emergency room immediately. Symptoms may include:

  • Bradycardia, hypotension, bronchospasm, acute cardiac failure, lethargy, wheezing, hypoglycaemia, sinus pause, disorder of respiratory drive.

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