Arsenic trioxide is a chemotherapeutic or antineoplastic agent which targets the enzyme thioredoxin reductase and causes morphological changes and DNA fragmentation in acute promyelocytic leukemia (APL) cells. It also breaks down and disrupts the fusion of promyelocytic leukemia (PML)-retinoic acid receptor (RAR)-alpha, thus inducing cancer cells to undergo apoptosis.
Use this medication precisely as recommended by your physician. Follow the prescription of your doctor carefully.
The medication dose given by your physician is based on your health conditions, other medications or food supplements taken, and your reaction to the treatment. To diminish risks for adverse effects, do not increase your dosage, thus take it regularly, or take it as instructed by your physician. Adverse events may still happen even at usual prescription dosages.
If your physician requests you to use this drug consistently, take it regularly to get the most benefits from it. To make you remember it better, take it at a fixed time every day.
Your doctor may need to modify your dosages to ease your symptoms or if you develop adverse reactions.
