Craniosynostosis is when the skull bones to fuse together prematurely in Aspert syndrome. As the brain continues to grow inside the abnormal skull, it puts pressure on the bones in the skull and face.
The abnormal skull and facial growth in Apert syndrome produce its main signs and symptoms:
- A head that is long, with a high forehead
- Wide-set, bulging eyes, often with poorly-closing eyelids
- A sunken middle face
Other Apert syndrome symptoms also result from the abnormal skull growth:
- Poor intellectual development (in some children with Apert syndrome)
- Obstructive sleep apnea
- Repeated ear or sinus infections
- Hearing loss
Abnormal fusion of the bones of the hands and feet (syndactyly) — with webbed or mitten-like hands or feet — are also common Apert syndrome symptoms. Some children with Apert syndrome also have heart, gastrointestinal, or urinary system problems.