Antimitochondrial antibodies are antibodies released by the immune system to attack the body. The mitochondria are the powerhouse of the cell, they are the ones responsible for creating energy to be used by cells inside the body. It makes the mitochondria a critical part of normal cell functions.
Like any other parts and organs of the body, an autoimmune response affects the mitochondria. It results from the immune system breaking down and attacking the body’s cells, tissues, and organs.
These antibodies are known to be associated with primary biliary cholangitis, which is formerly known as primary biliary cirrhosis. It is a chronic autoimmune disease characterized by the inflammation and scarring of the bile ducts inside the liver. There is yet no known cure for this condition, but treatment plans may help ease the symptoms and slow down the disease’s progression.
An antimitochondrial antibody test is conducted to identify the levels of antimitochondrial antibodies in the blood and diagnose primary biliary cholangitis.