ANASTROZOLE - Watsons Health

ANASTROZOLE

GENERIC NAME(S): ANASTROZOLE

 

Description: Anastrozole prevents conversion pathway for the hormones estrone and testosterone, thus reduceing serum estradiol concentrations

Anastrozole is used to treat breast cancer in menopausal women. It lowers estrogen hormone levels to help shrink tumors and slow their growth.

How to use anastrozole

Take by mouth with or without food, usually once a day, or as directed by your doctor, do not increase your dose or take more medication than the prescription.

Pregnant women or who may become pregnant should not handle or break the tablets of this medication.

Common side effects include: Constipation, diarrhea, nausea, vomiting, upset stomach, loss of appetite, body aches and pains, breast swelling/tenderness/pain, headache, dry mouth, scratchy throat, increased cough, dizziness, trouble sleeping, tiredness/weakness, flushing and sweating (hot flashes/hot flushes), vaginal bleeding, hair thinning, and weight change can occur.

Serious side effects occur: mental/mood changes (e.g., depression), excessive thirst, numbness/tingling/swelling of the hands or feet, unusual tickling feeling, persistent cough, unusual vaginal discharge/burning/itching/odor, unusually stiff muscles, muscle pain, joint stiffness/pain, pain/redness/swelling of the arms or legs, vision changes, bone pain, bone fracture, signs of infection (e.g., fever, chills, persistent sore throat), chest pain, jaw/left arm pain, trouble breathing, confusion, fainting, slurred speech, weakness on one side of the body.

Contact your doctor if you experience allergic reactions or symptoms mentioned above.

Precautions

Inform your doctor or pharmacist your allergies, medical history, especially of: liver disease, high blood pressure, heart disease (such as ischemic heart disease, history of chest pain), brittle bone disease (osteoporosis), blood clots.

Avoid activities that require alertness as this drug can make you dizzy.

Pregnant and breastfeeding women must consult their doctor first before using this medication.

If you have not gone through menopause and your doctor has prescribed this for you, this medication must not be used during pregnancy.

This medication may increase your risk of osteoporosis.  Be sure to eat a balanced diet, enough physical activity and calcium and vitamin D supplements if necessary.

 

Interactions

Serious interactions may occur: estrogens, tamoxifen.

Overdose

Get emergency medical help when overdose is suspected.

Missed Dose: As soon as you remember, take a regular dose or if the time of the next does is near, wait for it before taking another dose and resume your usual schedule.  Do not increase the dose to compensate for the missed dose.

Storage: Store medication in room temperature.  Do not expose to light and moisture. Do not store in the bathroom. Keep all medications away from pets and children.  Do not flush medications down the toilet or pour into a drain.

 

Brands

Available Brands

  • Anarom [ Sun Pharma ]
  • Anastroplex [ Teva ]
  • Anazole [ Biomedis Oncology ]
  • Arimidex [ AstraZeneca ]
  • Femizet [ Fresenius Kabi ]
  • Vexal-A [ VE Pharma ]

Also marketed as

  • Anzol [ Naprod ]
  • Astrozol [ Intas ]

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