Watsons Health


Ampicillin-Sulbactam is a combination drug that is utilized to treat bacterial infections. It is known as a antimicrobial similar to a penicillin. It works by halting the growth of bacteria.

This medicine is given by infusion into a vein, typically every six hours or as instructed by your physician. The dose depends on your disease and reaction to treatment. For children, the dose is additionally based on weight.

Ampicillin Sulbactam is used in the following:

  • Infections due to beta-lactamase producing H. influenzae including those of the respiratory tract, bones, joints and soft tissues
  • Polymicrobial infections with mixed aerobic and anaerobic such as, diabetic foot, gynecological infections, intra-abdominal infections
  • UTI due to susceptible organisms

Do not give Ampicillin Sulbactam to people with the following conditions:

  • History of allergic reaction to any of the penicillins

Ampicillin Sulbactam may have the following side effects:

  • Anaphylactoid reaction and anaphylactic shock
  • Diarrhea/loose stool
  • Nausea
  • Vomiting
  • Epigastric distress and abdominal cramps
  • Anemia
  • Hemolytic
  • Anemia
  • Thrombocytopenia
  • Eosinophilia and leucopenia
  • Transient elevations of ALT (SGPT) and AST (SGOT) transaminases
  • Bilirubinemia
  • Abnormal hepatic function
  • Jaundice
  • Rash

Take extra caution in patients with the following medical conditions:

  • Serious and occasionally fatal hypersensitivity (anaphylactic) reactions
  • Pregnancy
  • Lactation


Ampicillin Sulbactam may interact with the following medicines:

  • Allopurinol
  • Aminoglycosides
  • Chloramphenicol
  • Erythromycin
  • Sulfonamides
  • Tetracycline
  • Methotrexate

Symptoms of overdose include the following:

  • Neurologic effects, including seizures

Seek medical help immediately.

Available Brands:

  • Ampicare
  • Amsulvex

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