Amlodipine + Valsartan is a combination drug that is made up of amlodipine and valsartan.
Amlodipine, a dihydropyridine calcium channel blocker, decreases peripheral vascular resistance and blood pressure by creating peripheral blood vessel vasodilation through the blockade of calcium ion transmembrane influx into cardiovascular and vascular smooth muscles. Valsartan, a nonpetide tetrazole derivative, is an angiotensin II type 1 (AT1) receptor antagonist creating its blood pressure lowering ability by selectively blocking the binding of angiotensin II to angiotensin type 1 (AT1) receptors on various tissues including vascular smooth muscles and the adrenal gland, thereby resulting in antagonism of AT1-induced vasoconstriction, aldosterone synthesis and release, cardiac stimulation, and sodium renal reabsorption.
Use this medication precisely as recommended by your physician. Follow the prescription of your doctor carefully.
The medication dose your physician has given is based on your condition, other medications or food supplements you may take, and your reaction to treatment. To diminish your risks for adverse effects, don’t increase your dosage, take it regularly, or take it as instructed by your physician. Adverse events may still happen even at usual prescription dosages.
If your physician requests you to use this drug consistently, use it regularly to get the most benefits from it. To make you remember it better, take it at a fixed time every day.
Your doctor may need to modify your dosages to ease your symptoms or if you develop adverse reactions.
If you have any inquiries with regards to information, ask your physician or pharmacist.