AMLODIPINE + VALSARTAN- Uses, Warnings, Precautions,Overdose
Watsons Health

AMLODIPINE + VALSARTAN

Amlodipine + Valsartan is a combination drug that is made up of amlodipine and valsartan.

Amlodipine, a dihydropyridine calcium channel blocker, decreases peripheral vascular resistance and blood pressure by creating peripheral blood vessel vasodilation through the blockade of calcium ion transmembrane influx into cardiovascular and vascular smooth muscles. Valsartan, a nonpetide tetrazole derivative, is an angiotensin II type 1 (AT1) receptor antagonist creating its blood pressure lowering ability by selectively blocking the binding of angiotensin II to angiotensin type 1 (AT1) receptors on various tissues including vascular smooth muscles and the adrenal gland, thereby resulting in antagonism of AT1-induced vasoconstriction, aldosterone synthesis and release, cardiac stimulation, and sodium renal reabsorption.

Use this medication precisely as recommended by your physician. Follow the prescription of your doctor carefully.

The medication dose your physician has given is based on your condition, other medications or food supplements you may take, and your reaction to treatment. To diminish your risks for adverse effects, don’t increase your dosage, take it regularly, or take it as instructed by your physician. Adverse events may still happen even at usual prescription dosages.

If your physician requests you to use this drug consistently, use it regularly to get the most benefits from it. To make you remember it better, take it at a fixed time every day.

Your doctor may need to modify your dosages to ease your symptoms or if you develop adverse reactions.

If you have any inquiries with regards to information, ask your physician or pharmacist.

Amlodipine + Valsartan is used in the following conditions:

  • Hypertension

This medicine may be recommended for different uses. Approach your physician or pharmacist for more information.

  • Do not useAmlodipine + Valsartan in people with the following conditions:
  • Biliary cirrhosis or cholestasis
  • Concomitant use withACE inhibitors or aliskiren-containing product in patients with diabetes mellitus or renal impairment (CrCl <60 mL/min)
  • Pregnancy
  • Severe hepatic impairment
  • Severe hypotension
  • Shock

Amlodipine + Valsartan may have the following side effects:

  • Acute renal failure
  • Angina
  • Angioedema
  • Anorexia
  • Hyperkalaemia
  • Hypotension
  • Increased BUN
  • Influenza
  • Nasopharyngitis
  • Orthostatic hypotension
  • Paraesthesia
  • Peripheral oedema
  • Pitting and facial oedema

Keep in mind that your physician has recommended this drug since he or she has known that the advantage to you is more noteworthy than the risk of adverse reactions. Many individuals utilizing this medicine don’t have serious side effects.

A serious allergy to this medication is uncommon. In any case, seek emergency medical help if you see any manifestations of a serious allergic response, including a rash, tingling or swelling particularly of the face or tongue or throat, dizziness or difficulty in breathing.

This is is not a complete list of side effects. If you see other effects not recorded above, contact your physician or pharmacist.

Take extra caution in patients with the following medical conditions:

  • Biliary obstructive disorders
  • Chronic kidney disease
  • Diabetes mellitus
  • Idiopathic or hereditary angioedema
  • Lactation
  • Patient undergoing surgery or dialysis
  • Patient withNa- or volume-depletion
  • Primary hyperaldosteronism
  • Severe obstructive coronary artery disease

Prior to taking this medicine, tell your physician or pharmacist if you are allergic to it, or if you have some other hypersensitivities. This drug may contain inert ingredients which can cause unfavorable side effects or different issues. Talk with your pharmacist for more information.

 

Interactions

Amlodipine + Valsartan may interact with the following medicines:

  • Aliskiren
  • Clarithromycin
  • Closporin
  • Diltiazem
  • Diuretics
  • Erythromycin
  • NSAIDs
  • Ritonavir
  • TCAs
  • Verapamil

Inform your physician about the drugs you take including over-the-counter medications, prescribed drugs, supplements and vitamins.

This is not a complete list of drug interactions. Approach your physician or pharmacist for more details.

The effects of certain medications can change if you consume different medications or herbal products simultaneously. This can build your risk for side effects or may cause your drugs not to work effectively. These interactions are conceivable, yet don’t generally happen. Your physician or pharmacist can prevent or oversee interactions by changing how you utilize your prescriptions or by close checking.

While utilizing this drug, don’t start, stop, or change the dose of other medicines you are using without your physician’s advice.

If you think you have used Amlodipine + Valsartan more than the usual dosage, please seek medical help immediately.

 

Available Brands:

  • Amloval
  • Exforge
  • Trivan Plu
  • ValazydAM
  • Valcamp
  • Valianz
  • Valsar Plu
  • Valvex A

Related Articles

URSODEOXYCHOLIC ACID

Ursodeoxycholic acid is a medication that lowers cholesterol levels by controlling  hepatic synthesis and blocking intestinal absorption of cholesterol. Use [...]

UROKINASE

Urokinase is an enzyme derived from human urine that activates plasmin from plasminogen. The converted plasmin which is a proteolytic [...]

LEVODOPA

Levodopa is a prodrug of dopamine which is capable of crossing the blood brain barrier that results in increased dopamine [...]