AMLODIPINE + ATORVASTATIN

Amlodipine + Atorvastatin is a combination drug that is composed of amlodipine and atorvastatin

Amlodipine is a dihydropyridine calcium channel blocker which relaxes the peripheral and coronary vascular smooth muscles. It produces coronary vasodilation by blocking the passage of calcium ions into the voltage-gated channels of the vascular smooth muscle and myocardium during depolarization. It decreases peripheral vascular resistance and thus bringing about a decrease in blood pressure. In vasospastic angina, amlodipine likewise hinders coronary spasm in patients with vasopastic angina. Atorvastatin selectively and competitively blocks HMG-CoA reductase, the enzyme that catalyzes the conversion of HMG-CoA to mevalonate which is a rate-determining step in cholesterol synthesis.

Use this medication precisely as recommended by your physician. Follow the prescription of your doctor carefully.

The medication dose your physician has given is based on your condition, other medications or food supplements you may take, and your reaction to treatment. To diminish your risks for adverse effects, don’t increase your dosage, take it regularly, or take it as instructed by your physician. Adverse events may still happen even at usual prescription dosages.

If your physician requests you to use this drug consistently, use it regularly to get the most benefits from it. To make you remember it better, take it at a fixed time every day.

Your doctor may need to modify your dosages to ease your symptoms or if you develop adverse reactions.

If you have any inquiries with regards to information, ask your physician or pharmacist.

Uses

Amlodipine + Atorvastatin is used for the following conditions:

Hyperlipidaemia
Hypertension or angina

This medicine may be recommended for different uses. Approach your physician or pharmacist for more information.

Warnings

Do not use Amlodipine + Atorvastatin in people with the following conditions:

Active liver disease or unexplained persistent elevated hepatic transaminases
Lactation
Pregnancy

Side Effects

Amlodipine + Atorvastatin may have the following side effects:

Arthralgia
Asthenia
Bullous rashes
Dizziness
Flushing
Headache
Increased creatinine phosphokinase
Increased transaminases
Muscle spasms
Musculoskeletal pain
Nasopharyngitis
Palpitations
Peripheral edema
Rhabdomyolysis with acute renal failure

Keep in mind that your physician has recommended this drug since he or she has known that the advantage to you is more noteworthy than the risk of adverse reactions. Many individuals utilizing this medicine don’t have serious side effects.

A serious allergy to this medication is uncommon. In any case, seek emergency medical help if you see any manifestations of a serious allergic response, including a rash, tingling or swelling particularly of the face or tongue or throat, dizziness or difficulty in breathing.

This is is not a complete list of side effects. If you see other effects not recorded above, contact your physician or pharmacist.

Precautions

Take extra caution in patients with the following medical conditions:

Atorvastatin may cause myopathy
Caution in patients who consume large amounts of alcohol or witha history of liver disease
Caution in patients with severe aortic stenosis
Elderly
Patients with severe obstructive coronary artery disease

Prior to taking this medicine, tell your physician or pharmacist if you are allergic to it, or if you have some other hypersensitivities. This drug may contain inert ingredients which can cause unfavorable side effects or different issues. Talk with your pharmacist for more information.

Interactions

Amlodipine + Atorvastatin may interact with the following medicines:

Clarithromycin
Cyclosporine
Cyclosporine
Ethinyl estradiol
Itraconazole
Norethindrone
Rifamycins

Inform your physician about the drugs you take including over-the-counter medications, prescribed drugs, supplements and vitamins.

This is not a complete list of drug interactions. Approach your physician or pharmacist for more details.

The effects of certain medications can change if you consume different medications or herbal products simultaneously. This can build your risk for side effects or may cause your drugs not to work effectively. These interactions are conceivable, yet don’t generally happen. Your physician or pharmacist can prevent or oversee interactions by changing how you utilize your prescriptions or by close checking.

While utilizing this drug, don’t start, stop, or change the dose of other medicines you are using without your physician’s advice.

Overdose & Brands

If you think you have used Amlodipine + Atorvastatin more than the usual dosage, please seek medical help immediately.

You may exhibit the following symptoms in the event of an overdose:

Hypotension
Reflex tachycardia

Available Brands:

Lipend
Lodivas
Miravast
Nordin
Norvasc
Stalip-A/S