AMIKACIN SULFATE - Uses Warning Side Effects Precautions Overdose and Brands - Watsons Health
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AMIKACIN SULFATE

Amikacin sulfate is a medicine that is an aminoglycoside antibiotic. It is active against a wide range of microorganisms such as Gram-negative bacteria. It acts to inhibit protein synthesis in bacteria by binding to the 50s ribosomal subunit. This medicine is available as an injection.

Amikacin sulfate is used in the following conditions:

  • Severe Gram -negative bacterial infections
  • Uncomplicated UTI

Do not give Amikacin sulfate to people with the following conditions:

  • Hypersensitivity to amikacin and other aminoglycosides
  • Myasthenia gravis

Amikacin sulfate may have the following side effects:

  • Neurotoxicity manifested as vestibular and permanent bilateral auditory ototoxicity
  • Skin rash
  • Drug fever
  • Headache
  • Paresthesia
  • Nausea and vomiting
  • Eosinophilia
  • Arthralgia
  • Anaemia
  • Nephrotoxicity
  • Neuromuscular blockade and respiratoryparalysis
  • Clostridium difficile-associated colitis

Precautions

Take extra caution in patients with the following medical conditions:

  • Patient with pre-existing hearing or vestibular damage
  • Muscular disorder such as parkinsonism
  • Renal impairment
  • Premature and neonatal infants
  • Pregnancy
  • Lactation

 

Interactions

Amikacin sulfate may interact with the following medicines:

Symptoms of overdosage include the following:

  • Nephrotoxicity
  • Ototoxicity
  • Neuromuscular blockade and respiratoryarrest

Seek medical help immediately.

 

Available Brands:

Amicare, Amicyn, Amikacide, Cinmik, Kormakin, Phil Pharmawealth, Kamin, Mican, Mikalogis, Mikasul, Nica, Panmikin

 

 

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