AMBRISENTAN - Uses, Warnings, Side effects, Precautions
HUMAN PAPILLOMAVIRUS 9-VALENT VACCINE

AMBRISENTAN

The endothelin antagonist, Ambrisentan, is a selective receptor for endothelin type A (ETA). Endothelin is a potent vasoconstrictor for pulmonary arterial hypertension that plays a pathogenic role (PAH). Endothelin receptor blockade contributes to vasodilation and smooth muscle proliferation inhibition.

Use this medication precisely as recommended by your physician. Follow the prescription of your doctor carefully.

The medication dose given by your physician is based on your health conditions, other medications or food supplements taken, and your reaction to the treatment. To diminish risks for adverse effects, do not increase your dosage, thus take it regularly, or take it as instructed by your physician. Adverse events may still happen even at usual prescription dosages.

If your physician requests you to use this drug consistently, take it regularly to get the most benefits from it. To make you remember it better, take it at a fixed time every day.

Your doctor may need to modify your dosages to ease your symptoms or if you develop adverse reactions.

Ambrisentan is used in the following conditions:

  • Pulmonary arterial hypertension

This medicine may be recommended for different uses. Approach your physician or pharmacist for more information.  

Do not use Ambrisentan in people with the following conditions:

  • Idiopathic pulmonary fibrosis
  • Severe hepatic impairment or clinically significant elevated hepatic aminotransferases (>3 times the upper limit of normal)
  • Pregnancy
  • Lactation

Ambrisentan has no reported side effects.

Precautions

Take extra caution in patients with the following medical conditions:

  • Autoimmune hepatitis 
  • Reduced hemoglobin and hematocrit
  • Fluid retention
  • Peripheral edema
  • Acute pulmonary edema
  • Decreased sperm count
  • Headache
  • Dizziness
  • Fatigue
  • Asthenia
  • Palpitation
  • Cardiac failure
  • Flushing
  • Hypotension
  • Syncope
  • Chest pain
  • Diarrhea
  • Vomiting
  • Nausea
  • Abdominal pain
  • Constipation
  • Dyspnea
  • Nasopharyngitis
  • Nasal congestion
  • Epistaxis
  • Sinusitis
  • Rhinitis

Prior in taking this medicine, tell your physician or pharmacist if you have allergies  or other hypersensitivity reactions with the drug. This drug may contain inert ingredients which can cause unfavorable side effects or different issues. Talk with your pharmacist for more information.

Interactions

Ambrisentan may interact with the following medicines:

  • Ciclosporin
  • Rifampicin

Inform your physician about the drugs you take including over-the-counter medications, prescribed drugs, supplements and vitamins.

This is not a complete list of drug interactions. Approach your physician or pharmacist for more details.

The effects of certain medications can change if you consume different medications or herbal products simultaneously. This can build your risk for side effects or may cause your drugs not to work effectively. These interactions are possible, yet don’t generally happen. Your physician or pharmacist can prevent or oversee interactions by changing how you utilize your prescriptions or by close checking.

While utilizing this drug, don’t start, stop, or change the dose of other medicines you are using without your physician’s advice.

If an overdose is suspected, call your health care provider immediately.

Available brands:

  •  Letairis

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