ACICLOVIR-Uses, Warnings, Side Effects, Precautions, Overdose and Brands


Aciclovir is an antiviral drug that is changed over to monophosphate by thymidine kinase that is specific for viruses then additionally changed over to triphosphate by other cell catalysts. This drug restrains DNA synthesis and viral replication by contending with deoxyguanosine triphosphate for viral DNA polymerase and being fused into viral DNA.

This drug is known as an antiviral drug and is used to treat herpes zoster or shingles. However, this drug cannot treat herpes virus infections completely but only lessens the viral load in the body. This drug facilitates faster healing of lesions, prevents new complications and lessens the pain or itchiness associated with the disease. In some cases, aciclovir helps people with weak immune systems prevent viruses from spreading in the different areas of the body. This drug can be in the form of a tablet, syrup or cream.

Aciclovir is used in the following conditions:

  • Recurrent herpes labialis
  • Prophylaxis of herpes simplex in immunocompromised patients
  • Herpes simplex encephalitis
  • First episodes of genital herpes
  • Varicella-zoster virus infection
  • Neonatal herpes simplex virus infections
  • Herpes simplex keratitis

Do not use Aciclovir in people with the following conditions:

  • Hypersensitivity to aciclovir and valaciclovir

Side Effects


These side effects are common and can be managed; but if they get worse, seek medical attention immediately:

  • Diarrhea
  • Nausea
  • Vomiting
  • Headache


Immediate medical attention is needed when these side effects happen:


  • Dizziness
  • Changes in the amount of urine
  • Unbearable back/side pain l
  • Mood swings
  • Unstable movements
  • Problem in speaking
  • Drowsiness

The list above is not complete. There are many side effects of aciclovir that you should know about. If unusual things happen while taking this drug, consult a doctor or pharmacist.


There are certain circumstances that you should consider before you undergo treatment. Consult your doctor or pharmacist regarding your allergies. There may be some ingredients in this medicine that can cause allergic reactions. Also, tell your doctor if you have a history of kidney problems, conditions that are related to a weak immune system (such as HIV infection, bone marrow transplant or a kidney transplant) and use of alcoholic beverages. Drug interactions can change the way your medication works; these can make side effects more severe. Consult your doctor about the other medicines that you are using, such as herbal products, prescription medicines or non-prescription drugs. You can stop or continue these medicines with a doctor’s guidance.

  • If you think you have used Aciclovir more than the usual dosage, please seek medical help immediately.Symptoms of overdose include the following:
    • Elevations in BUN and serum creatinine
    • Subsequent renal failure
    • Anuria
    • Agitation
    • Coma
    • Lethargy
    • Seizures

    Available Brands:

    • Cyclostad
    • Zovirax

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