Acetaminophen is used to relieve pain and reduce fever. Chlorpheniramine (CPM) is an antihistamine that helps relieve symptoms such as watery eyes; itchy eyes, nose, throat; runny nose; and sneezing. Dextromethorphan (DM) is a cough suppressant that reduces the urge to cough by affecting certain part of the brain.

This combination medication is used to treat symptoms such as pain, sinus congestion, runny nose, sneezing, and cough that are caused by colds, upper respiratory infections, and allergies. This medication may also be used in other conditions to be determined by your doctor.

Do not use this drug:

  • If you are allergic to any ingredient in it.
  • If you have severe high blood pressure, severe heart blood vessel disease, rapid heartbeat, or severe heart problems
  • If you are unable to urinate or are having an asthma attack
  • If you take Sodium Oxybate (GHB) or you have taken Furazolidone or a Monoamine Oxidase (MAO) inhibitor (eg, Phenelzine) within the last 14 days

Common side effects may include:

  • Drowsiness
  • Dry Eyes, Mouth
  • Loss of Appetite
  • Stomach Upset

Notify your doctor promptly if any of these symptoms persist or worsen.

Your doctor may have prescribed this medication because he or she judged that the benefit to you is greater than the risk of side effects.

Serious side effects may include:

  • Allergic Reactions Like Skin Rash, Itching or Hives, Swelling of the Face, Lips, or Tongue
  • Chest Pain, Tightness
  • Dizziness, Nervousness, or Sleeplessness
  • Fast, Irregular Heartbeat
  • Trouble Passing Urine or Change in the Amount of Urine
  • Unusual Bleeding or Bruising
  • Unusually Weak or Tired
  • Yellowing of the Eyes or Skin

Seek immediate medical attention if you experience any of these serious side effects.


Before taking this drug, tell your doctor or pharmacist:

  • If you are allergic to any content of this drug or if you have other allergies.
  • If you are pregnant, planning to become pregnant, or are breast-feeding
  • If you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • If you have a fast, slow, or irregular heartbeat
  • Your medical history, especially of: Your medical history, especially of:
    • Adrenal Gland Problems (eg, Adrenal Gland Tumor)
    • Heart Problems
    • High Blood Pressure
    • Diabetes
    • Heart Blood Vessel Problems
    • Stroke
    • Glaucoma
    • A Blockage of your Stomach
    • Bladder
    • Intestines
    • Ulcers
    • Trouble Urinating
    • An Enlarged Prostate or other Prostate Problems
    • Seizures
    • Overactive Thyroid
    • Liver Problems
    • Asthma
    • Chronic Cough, Lung Problems (eg, Chronic Bronchitis, Emphysema), or Chronic Obstructive Pulmonary Disease (Copd), or if your Cough Occurs with Large Amounts of Mucus
    • Use and Abuse of Alcohol



Drug interactions may either lessen the effectiveness of this drug or heighten the risk for severe side effects. It’s important to inform your doctor all the medication including prescription and non-prescription and herbal medicines you are taking or going to take.

Possible interactions with this drug are:

  • Cocaine
  • Ergot Alkaloids like Dihydroergotamine, Ergonovine, Ergotamine, Methylergonovine
  • Maois like Carbex, Eldepryl, Marplan, Nardil, and Parnate
  • Stimulant Medicines like Dextroamphetamine
  • Alcohol
  • Bretylium
  • Furazolidone
  • Imatinib
  • Isoniazid
  • Linezolid
  • Mecamylamine
  • Medicines for Anxiety or Sleep
  • Medicines for Blood Pressure like Atenolol, Clonidine, Doxazosin, Methyldopa, Metoprolol
  • Medicines for Chest Pain like Isosorbide Dinitrate, Nitroglycerin
  • Medicines for Enlarged Prostate like Tamsulosin
  • Medicines for Sleep During Surgery
  • Other Medicines for Cold, Cough or Allergy
  • Other Medicines with Acetaminophen
  • Procarbazine
  • Reserpine
  • John’s Wort

Call emergency hotline if someone has overdosed and has serious symptoms such as passing out or trouble breathing.

Symptoms of overdose may include:

  • Blurred Vision
  • Confusion
  • Hallucinations
  • Seizures
  • Severe Dizziness
  • Lightheadedness or Headache
  • Severe Drowsiness
  • Unusually Fast, Slow, or Irregular Heartbeat
  • Vomiting

Available brand/s:

  • Colvan
  • Congestril
  • Dynatussin
  • Mucotuss
  • Triplec P Capsule

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