Aspirin is a salicylate that treats pain and reduces fever or inflammation. Acetaminophen is also used to relieve pain and reduce fever. Caffeine is a stimulant and works by relaxing the muscle contractions in blood vessels to improve blood flow. Salicylamide have analgesic and antipyretic properties and works like an Aspirin.

This combination medication is used to temporarily relieve pain in headache; backache; muscular aches, and minor arthritis that are may be caused by the common cold, toothache or menstrual cramps.

Do not use this drug:

  • To children younger than 18 years unless specifically prescribed by the doctor.
  • More than prescribed. Taking too much Acetaminophen may damage your liver. Too much caffeine can also result into unwanted side effects.

This drug may cause dizziness, drowsiness or blurred vision. Avoid activities requiring alertness or clear vision such as driving until you are sure you can perform such activities safely. Limit the use of alcohol and certain other medications that cause drowsiness.

Common side effects may include:

  • Dry Mouth
  • Nervousness, Irritability, or Trouble Sleeping
  • Ringing in your Ears, or Loss of Hearing
  • Unusual Tiredness or Drowsiness
  • Warmth or Redness in your Face, Neck, Arms, or Upper Chest

Notify your doctor promptly if any of these symptoms persist or worsen.

Your doctor may have prescribed this medication because he or she judged that the benefit to you is greater than the risk of side effects.

Serious side effects may include:

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Change in how much or how often you urinate
  • Dark urine or pale stools, nausea, vomiting, loss of appetite, or stomach pain, yellow skin or eyes
  • Fast or uneven heartbeat
  • Unusual bleeding, bruising, or weakness

Seek immediate medical attention if you experience any of these serious side effects.


Before taking this drug, tell your doctor or pharmacist:

  • If you are allergic to any content of this drug or if you have other allergies.
  • If you are pregnant, planning to become pregnant, or are breast-feeding
  • If you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • If you have a history of alcohol abuse or if you consume 3 or more alcohol-containing drinks every day
  • If you have certain medical conditions such as:
    • Asthma
    • Bleeding or Clotting Problems
    • Growths in the Nose (Nasal Polyps)
    • Kidney or Liver Problems (eg, Cirrhosis)
    • Hepatitis
    • High Blood Pressure
    • Heart Problems
    • Influenza (Flu) or Chickenpox
    • Vitamin K Deficiency
    • Anxiety
    • Trouble Sleeping
  • If you have or have a history of stomach or peptic ulcers (bleeding ulcers) or other stomach problems (eg, heartburn, upset stomach, stomach pain)
  • If the patient is a child with a stroke, a weakened blood vessel (cerebral aneurysm) or bleeding in the brain, or Kawasaki syndrome (a rare inflammation causing heart problems in children)



Drug interactions may either lessen the effectiveness of this drug or heighten the risk for severe side effects. It’s important to inform your doctor all the medication including prescription and non-prescription and herbal medicines you are taking or going to take.

Possible interactions with this drug are:

  • A blood thinner, such as warfarin
  • Combination medicines that contain acetaminophen or aspirin
  • Other medicines that contain caffeine, such as some diet pills and pain relievers
  • Phenobarbital
  • Alcohol

Call emergency hotline if someone has overdosed and has serious symptoms such as passing out or trouble breathing.

Symptoms of overdose may include:

  • Dark Urine
  • Excessive Sweating
  • Extreme Fatigue
  • Irregular Heartbeat
  • Low Blood Pressure
  • Stomach Pain
  • Vomiting
  • Yellowing of the Skin or Eyes

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