ABCIXIMAB

Commonly reported

• Major hemorrhage or hemorrhage, chest pain, hypotension, nausea, back pain.

Minor side effects (if these symptoms persist or worsen, inform your doctor)

• Back pain, acid or sour stomach, belching, burning, crawling, itching, numbness, prickling, “pins and needles”, or tingling feelings, changes in vision, delusions, dementia, fear, heartburn, indigestion or stomach discomfort, upset or pain, mood or mental changes, nausea, nervousness, vomiting.

Serious side effects (inform your doctor immediately)

• Bleeding, blurred vision; confusion; dizziness, faintness, or lightheadedness when getting up from a lying or sitting position suddenly; sweating; unusual tiredness or weakness, black, tarry stools, bleeding gums,blood in urine or stools, pinpoint red spots on skin, unusual bleeding or bruising.
• May rarely cause: Chest pain or discomfort, chills, cough, eye pain, fever, general feeling of illness, headache, pale skin, rapid weight gain, shortness of breath, slow or irregular heartbeat, sneezing, sore throat, swelling of hands, ankles, feet, or lower legs, tightness in chest, tingling of hands or feet, troubled breathing, unusual tiredness, wheezing.

Precautions

• Inform your doctor if you have/experienced:
  • Allergy to medicne or any other allergies i.e. to mouse proteins.
  • Current bleeding, bleeding from the gut or bladder in the last 6 weeks (e.g., bleeding peptic ulcer), stroke in the last 2 years, history of stroke with continuing problems (e.g., slurred speech, weak muscles, vision problems), major surgery/injury/other bleeding in the last 6 weeks, brain tumor, blood vessel problem in the brain (e.g., aneurysm, AV malformation), very high uncontrolled blood pressure, inflammation of the blood vessels (vasculitis).
• Tell your doctor your medical history, especially of:
  • Use of this drug in the last 30 days
  • Stomach/intestinal problems (e.g., peptic ulcer, inflammatory bowel disease)
  • Low blood platelets (thrombocytopenia)
  • Liver disease
• Consult doctor if pregnant or breastfeeding.

Drug Interactions

Taking multiple drugs may affect how medications work and/or cause unwanted side effects. List down all the medications you are taking and inform your physician and pharmacist. Do not take, discontinue, or alter any dose of medications without prior approval of your physician.

• This drug should not be used with the following medication because a very serious interaction may occur: dextran.
  • If you are currently using the medication listed above, tell your doctor or pharmacist before starting abciximab.
• Tell your doctor about your medications especially about:
  • Other “blood thinners” (e.g., warfarin) used in the last 7 days, NSAIDs (e.g., ibuprofen, naproxen), anti-platelet drugs (e.g., dipyridamole, ticlopidine), tipranavir.

If overdose is suspected, contact a local poison control center or emergency room immediately.

Laboratory and/or medical tests (e.g., bleeding times, platelet count) should be performed periodically to monitor your progress or check for side effects

Missed Dose: If your dose is stopped or interrupted, contact the doctor immediately to establish a new dosing schedule/rate.

Storage

• Refrigerate between 2-8 degrees C (36-46 degrees F)
• Do not freeze
• Discard any unused liquid
• Keep all medicines away from children and pets
• Do not flush medications down the toilet or pour them into a drain unless instructed to do so.
• Properly discard this product when it is expired or no longer needed